Forget about Agile and Scrum on the team level. Start with the org. Visualize the work as it is really happening … with all the gnarly dependencies. Have 150 person stand ups if that is the true size of the team. Have 150 people vote up the blockers that really matter, and swarm to fix those blockers. Face the mess head on, iterate, and improve. Rapidly rotate and reform teams to dynamically address the biggest blockers. Don’t hire human load balancers to preserve the status quo. Focus on DevOps, tooling, infrastructure, and unraveling the political bureaucracy that over-burdens and overutilizes the teams.